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Relapsing and Remitting Human Immunodeficiency Virus-Associated Leukoencephalomyelopathy
Ann Neurol 31:34-38, Berger,J.R.,et al, 1992
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Article Abstract
We describe a 33-year-old homosexual man with a steroid-responsive, remitting and relapsing leukoencephalopathy associated with recent human immunodeficiency virus type 1(HIV-1)seroconversion.Biopsy of a parieto- occipital lesion revealed demyelination and astrogliosis with focal necrosis.Detailed investigations demonstrated no pathogens in the brain other than HIV-1.This patient illustrates that a neurological disorder clinically indistinguishable from multiple sclerosis may be the presenting manifestation of HIV-1 infection and may occur in the absence of clinically significant immunosuppression.
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demyelinating disease
human immunodeficiency virus type 1
leukoencephalopathy
MRI
MRI,abnormal
multiple sclerosis
multiple sclerosis,differential diagnosis of
myelitis,transverse
myelopathy
optic neuritis
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