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Response of Carpal Tunnel Syndrome to Hormone Replacement Therapy
BMJ 303:1514, Confino-Cohen,R.,et al, 1991
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Article Abstract
The carpal tunnel syndrome is five times more common in women than in men; it is found most often in women aged over 40 and is therefore common postmenopausally.The ultimate form of treatment is surgical relief of nerve entrapment.There is,however,general agreement that conservative measures should be tried first.These include mainly splinting,injection of steroids into the carpal tunnel,and nonsteroidal anti-inflammatory agents. Treatment with vitamin B-6 has also been advocated,but the therapeutic effect was not corroborated by controlled studies.We describe two women with severe carpal tunnel syndrome unresponsive to medical treatment,whose symptoms resolved unexpectedly soon after starting hormone replacement therapy for their menopausal symptoms.
 
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carpal tunnel syndrome
menopause
premarin
progesterone
pyridoxine
treatment of neurologic disorder

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