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Fast Magnetic Resonance Diffusion-Weighted Imaging of Acute Human Stroke Neurol 42:1717-1723, Warach,S.,et al, 1992 See this aricle in Pubmed Article Abstract Rapid MRI of the molecular diffusion of water demonstrated cerebral infarcts in 32 patients.We studied these patients ar various times following the onset of ischemic symptoms and found that diffusion-weighted imaging revealed the infarcts sooner than conventional T2-weighted spin- echo imaging did;four hyperacute infarcts were shown only by diffusion- weighted imaging.Acute infarcts had lower apparent diffusion coefficients (ADCs)than noninfarcted regions did.This relative difference in ADC reached a nadir in the first 24 hours and rose progressively thereafter. Chronic infarcts showed a relative increase in diffusion and were readily distinguishable from acute infarcts.The technique takes less than 2 minutes to apply using a standard 1.5-tesla scanner in the clinical setting.Diffusion-weighted imaging has the potential to play a role in improving the early anatomic diagnosis of stroke and therefore in the development and implementation of early stroke intervensions.

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(click to filter results - removes previous filter) cerebral infarction cerebrovascular accident MRI MRI,abnormal MRI,cerebrovascular disease MRI,diffusion weighted MRI,early changes in CVA MRI,fast

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