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We report a 74 year old woman with progressive cognitive deterioration and changes in personality.The had no clinical signs of an inflammatory CNS process,but brain CT and MRI scans and cytologic examination of the CSF were initially indicative of encephalitis and ventriculitis.Antiviral and antibacterial therapy had no effect on the course of symptoms and the patient became comatose.We established the diagnosis of a primary CNS mantle cell lymphoma(PCNSL)and began corticosteroids.Within a few days the patient became alert and was able to walk again.Nonenhancing and nonspace- occupying PCNSLs are rare but must be considered in the differential diagnosis of coma and encephalitis.Comatose PCNSL patients without radiographic evidence for herniation can be successfully treated with corticosteroids even of the EEG has a burst suppression pattern. |
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burst suppression pattern,electroencephalogram CAT scan CAT scan,abnormal CAT scan,contrast enhanced CAT scan,contrast enhanced,subepend. cerebrospinal fluid,elevated protein of coma electroencephalogram,abnormalities of hypoglycorrhachia lymphoma lymphoma involving CNS lymphoma,meningeal lymphoma,primary of CNS misdiagnosis pleocytosis of cerebrospinal fluid reactive pleocytosis steroid therapy,CNS treatment and complications with
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