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Dentate Nuclei Invol in AIDS Pts with CNS Cryptococcosis:Imaging Findings with Path Correl
J Comput Assist Tomogr 21:175-182, Ruiz,A.,et al, 1997
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Article Abstract
Five of 11 patients were found at autopsy to have macroscopically visible" cystic"lesions in the dentate nuclei that were not detected on CT(10 patients),but were seen on premortem MR(1 patient).Macroscopic supratentorial(basal ganglia,thalamic,midbrain)lesions were detected by CT in 5 of 11 patients and by MR in 2 of 2 patients.Enhancement of the leptomeninges was seen in only 1 patient by CT despite pathological evidence of cryptococcal meningitis in all 11 patients.Dilated Virchow- Robin spaces were seen in all 11 pathologic specimens and in the 2 MR studies but not on CT.Communicating hydrocephalus was detected by CT in two patients.CT scans of the brain underestimate infratentorial parenchymal cryptococcal disease.MR is a more sensitive procedure to evaluate cerebellar and brainstem cryptococcosis,including the dentate nuclei,white in our autopsy series was not an uncommon site to be infected with cryptococcal gelatinous pseudocysts.
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acquired immunodeficiency syndrome
CAT scan
CAT scan,abnormal
cryptococcal meningitis
cryptococcosis
dentate nuclei
dentate nuclei,lesion of
hydrocephalus
MRI
MRI,abnormal
MRI,CAT scan compared to
neuropathology
pheochromocytoma
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