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The Clinicopathological Spectrum of Rosenthal Fibre Encephalopathy and Alexanders Disease: A Case Report and Review of the Literature
JNNP 74:807-810, Jacob,J.,et al, 2003
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Article Abstract
In rare instances, numerous Rosenthal fibres have been found at autopsy in patients who have suffered protracted debilitating systemic illnesses, some with associated brain stem signs, and in very rare instances in patients with no apparent neurological abnormality. The term Rosenthal fibre encephalopathy is used to distinguish these cases from those of Alexanders disease. We report the first case of Rosenthal fibre encephalopathy in a young man with AIDS, and review the literature.
 
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acquired immunodeficiency syndrome
Alexanders disease
brainstem,dysfunction
brainstem,lesion of
encephalopathy
gene mutation
review article
Rosenthal fiber encephalopathy
Rosenthal fibers

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