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Reversible Blindness Secondary to Acute Sphenoid Sinusitis Otolaryngol Head Neck Surg 112:742-746, Postma,G.N.,et al, 1995 See this aricle in Pubmed Article Abstract Infection of the sphenoid sinus is an uncommon clinical entity frequently misdiagnosed because of its vague symptoms and paucity of clinical findings. The diagnosis is often delayed until the patient has a neurologic complication. We report a case that initially manifested as Gradenigos syndrome (petrous apicitis) but ultimately proved to be acute sphenoid sinusitis complicated by bilateral blindness. The patients vision returned to normal 48 hours after surgical decompression of the sinus and treatment with antibiotics. We strongly recommend early surgery in patients with acute sphenoid sinusitis when the surgeon believes there may be any possibility of an impending complication or if the patient does not clinically improve in 24 hours with medical therapy.

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