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Interferon beta for Secondary Progressive Multiple Sclerosis: A Systematic Review
JNNP 84:420-426, La Mantia, L.,et al, 2013
See this aricle in Pubmed

Article Abstract
3 year treatment with IFN? does not delay permanent disability in SPMS but reduces relapse risk, indicating that the anti-inflammatory effect of IFN? is unable to prevent MS progression once it has become established.
 
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