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The ears of the lynx sign on FLAIR MR imaging is highly specific for the most common genetic subtypes of hereditary spastic paraplegia with a thin corpus callosum. When this sign is present, there is a high likelihood of a genetic mutation, particularly associated with SPG11 or SPG15, even in the absence of a family history. |
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corpus callosum corpus callosum,atrophy of corpus callosum,thinning ears of the Lynx MR sign gene mutation genetic neurologic disorders intellectual deficit MRI,abnormal neurologic disease,diagnoses of paraparesis,familial spastic paraparesis,familial spastic,classification paraparesis,spastic spastic paraplegia,type 11 spastic paraplegia,type 15
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